英国博士招聘-萨塞克斯大学-“早期视觉系统中视觉和行为信号的整合”

发布时间：2020-11-17

浏览次数：723次

如有招聘信息发布(博士/博后/访学)可联系

邮箱：cxw@med.tj.cn

微信：shelver888

公众号链接：https://mp.weixin.qq.com/s?__biz=MzU5NTk2OTE2Mw==&mid=2247485830&idx=1&sn=98ac88e2946e77ee54d7a6de5cb9df08&chksm=fe689c62c91f15748ac51e0318bc4925c559d723f065b2c2e8c53ac68000c2b66cbb600ec94d&token=1637237711&lang=zh_CN#rd

学校：萨塞克斯大学 University of Sussex

院系：School of Life Sciences

教授：Sylvia Schröder

申请网址： https://southcoastbiosciencesdtp.ac.uk/

截止日期：January 4, 2021

　　介绍

SoCoBio的四年制博士培训计划下，Sylvia Schröder（https://www.sussex.ac.uk/research/labs/schroeder-lab/index）和Leon Lagnado（https://lagnadolab.com/）的实验室与他们的行业合作伙伴Scientifica合作提供了以下博士学位项目：

“在早期视觉系统中整合视觉和行为信号”。

在此项目中，您将了解视网膜，皮层和神经调节输入如何构成上丘脑的视觉神经元的反应。您的博士项目的目标是了解信号整合的机制，即上丘胶体的输入会影响其神经活动，以及这种整合在视觉处理中的优势。

对清醒的小鼠使用双光子成像，同时记录上丘脑神经元的活动，以及视网膜，视觉皮层或中缝背核（5-羟色胺）类的脑干核的轴突的活动。您将比较轴突输入与神经元中的反应，并观察这些信号如何根据视觉输入和动物行为而变化。

在项目开始时，您将与我们的行业合作伙伴Scientifica合作开发一种先进的成像技术。采用现有的双光子显微镜同时使两个单独的视野成像。这项称为多区域成像的技术将确保你能够详细的，及时的以及完整的记录上丘脑的输入和输出过程。

项目描述：https://southcoastbiosciencesdtp.ac.uk/project/integration-of-visual-and-modulatory-inputs-in-the-early-visual-system/

有关更多信息，请联系 sylvia.schroeder@ucl.ac.uk

　　申请

项目申请请点击：https://southcoastbiosciencesdtp.ac.uk/

　　Job description

Within SoCoBio‘s 4-year doctoral training program, the labs of Sylvia Schröder (https://www.sussex.ac.uk/research/labs/schroeder-lab/index) and Leon Lagnado (https://lagnadolab.com/) are offering the following Phd project in collaboration with their industrial partner, Scientifica:

“Integration of visual and behavioural signals in the early visual system”

In this project, you will discover how retinal, cortical and neuromodulatory inputs shape the responses of visual neurons in the superior colliculus. The goal of your Phd project is to understand the mechanisms of signal integration, i.e. which inputs to the superior colliculus shape its neural activity, and the advantages of this integration for visual processing.

You will use two-photon imaging in awake mice to simultaneously record activity of neurons in the superior colliculus as well as of axons originating in the retina, visual cortex, or brainstem nuclei such as the dorsal raphe (serotonin). You will compare the responses of the axonal inputs to those in the neurons, and you will observe how these signals change depending on the visual input and the behaviour of the animal.

In the beginning of your project, you will develop an advanced imaging technique in collaboration with our industrial partner, Scientifica. You will adapt the existing two-photon microscope to image two separate fields of view simultaneously. This technique, termed multi-region imaging, will enable you to record inputs and outputs of superior colliculus at sufficient detail, speed, and quantity.

Application to the program: https://southcoastbiosciencesdtp.ac.uk/

Project description: https://southcoastbiosciencesdtp.ac.uk/project/integration-of-visual-and-modulatory-inputs-in-the-early-visual-system/

For further information, contact sylvia.schroeder@ucl.ac.uk

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